On August 14, 2026, China’s National Healthcare Security Administration officially issued the Guidelines for Pricing Healthcare Service Items for Medical Testing (Trial). The guidelines introduce new pricing items for tumor tissue organoid culture and tumor organoid drug sensitivity testing, marking a further step toward integrating tumor organoid technologies into the national healthcare pricing framework and supporting their clinical translation and standardized application. At the core of organoid culture, one material remains indispensable—Matrigel.

As an essential 3D matrix, Matrigel provides cells with a culture environment that closely mimics the in vivo microenvironment. 

Therefore, Matrigel is widely used in organoid culture, stem cell culture, 3D culture, tumor models, angiogenesis, cell migration/invasion, and other research applications. As these applications continue to advance, researchers are looking beyond basic usability to consistent performance, batch-to-batch consistency, quality control, and reliable supply.

2. From 3D Matrices to Complete Workflow Reagents

To meet the growing needs of organoid and 3D cell culture, NEST continues to expand its product portfolio, covering 3D matrices and workflow reagents to provide researchers with more choices and comprehensive experimental support.

01 Matrigel: Building a 3D Culture Environment

GelNest Matrigel is an important part of NEST’s organoid product portfolio. It is currently available in multiple formulations:

Standard | Routine organoid culture, 3D culture, migration/invasion

Phenol Red-Free | Fluorescence imaging and detection

GFR | Cell differentiation and organoid research

GFR Phenol Red-Free | Differentiation, organoid culture, fluorescence detection

HC | High-strength 3D culture, organoids, invasion assays

HC Phenol Red-Free | High-strength 3D culture, organoids, fluorescence assays

hESC-Qualified | hESC culture and differentiation

Organoid-Specific | Organoid establishment, expansion and culture

From building the basic 3D culture environment to meeting different experimental needs, GelNest provides stable 3D matrix support for organoid research.

02 Complete Workflow Reagents

Beyond Matrigel, NEST also offers a range of cell culture and handling reagents to support organoid-related research.

Laminin

An important component of the extracellular matrix, Laminin plays a role in cell adhesion, migration and differentiation.

Applications: Primary neuron culture | Neural differentiation of stem cells | Cardiomyocyte differentiation

Mouse Tail Collagen I

As a major component of the extracellular matrix, Type I Collagen supports cell adhesion and matrix construction.

Applications: 2D/3D cell culture | Culture vessel coating | Gel scaffolds

Mouse Collagen IV

As a key component of the basement membrane, Type IV Collagen contributes to cell adhesion and microenvironment construction.

As a new addition to NEST’s organoid-related portfolio, it provides more options for organoid culture, 3D cell culture and basement membrane research.

03 Key Product Advantages

Stable Performance | Consistent protein concentration and good batch-to-batch consistency

Low Endotoxin | Strict control of endotoxin levels

Strict Quality Control | Comprehensive testing and traceable quality

Comparable Performance | Designed to benchmark imported products, supporting domestic alternatives

Reliable Supply | Scaled production for consistent and continuous supply

3. End-to-End Quality Control

Stable products start with a reliable manufacturing system. NEST implements multi-stage quality control from raw materials to finished products.

01 SPF Animal Center | Source Control

Standardized SPF-grade animal facilities help ensure consistent raw material quality and stable production.

02 Class 10,000 Cleanroom | Controlled Manufacturing

GelNest is manufactured in a Class 10,000 cleanroom with low-temperature control, cold-chain transportation and full-process traceability.

Capacity: >5 L/batch | >50 L/month

03 Comprehensive Testing | Quality Assurance

Each batch undergoes endotoxin, bacterial & mycoplasma, LDEV PCR, protein composition, gel stability, bioactivity and organoid culture testing, with complete COA and quality documentation provided.

From source to finished product, every step is controlled to ensure consistent quality, stable performance and reliable supply.

Back-to-School Research Offers

Campaign Period: Aug 16 – Sep 26, 2026

All Products: 10% OFF

Special offers on Matrigel:

5 mL Matrigel: Get a RMB 50 JD.com gift card

Redemption period: Aug 16 – Oct 7

10 mL or more: Enjoy an additional 20% OFF when purchasing one case of cell culture inserts/plates

Whether for organoid culture, 3D cell culture, or cell migration and invasion studies, NEST’s Back-to-School offers are here to support your research this new semester.

From Matrigel to a growing portfolio of cell culture reagents, NEST continues to expand its products and services around life science research needs, providing reliable support for organoid and cell culture research.