In biopharmaceutical and biologics manufacturing, large-volume liquid materials are involved throughout key processes such as media preparation, process scale-up, intermediate storage, and final product transfer.

NEST now introduces the 10 L PC Square Storage Bottle, providing a more reliable solution for production-scale liquid management.

01 Product Overview

The NEST 10 L PC Square Storage Bottle is a ready-to-use sterile liquid container specifically designed for pharmaceutical and biologics manufacturing. It is suitable for the aseptic storage, precise formulation, and safe transfer of critical liquids.

02 Product Advantages

1. Medical-grade materials with excellent resistance

·  Manufactured from medical-grade polycarbonate (PC)

· Non-cytotoxic and animal-origin free

·  Withstands –80 °C cryogenic storage

·  Supports 121 °C / 30 min autoclave sterilization

·  Cap made of PP with a silicone gasket, validated for repeated freeze–thaw cycles and sterilization

·  Stable structure with no deformation or leakage

2. Reliable sterility and regulatory compliance

·  Produced in a Class 100,000 clean environment and sterilized by electron beam, achieving SAL = 10⁻⁶

·  Pyrogen-free, nuclease-free, and low particulate levels

·  Double heat-sealed sterile packaging, compliant with GMP cleanroom material entry requirements

3. Optimized structural design

·  Narrow-neck design for accurate liquid control

·  Molded sidewall grooves for improved grip and pouring stability

·  Concave bottom design compatible with magnetic stirring

·  Cap with integrated silicone gasket ensures secure sealing and leak prevention

03 Applications

Preparation and aseptic storage of media and buffers

Storage of critical process intermediates and semi-finished products

Closed and safe transfer of process fluids

04 Advanced Manufacturing Technology

NEST adopts internationally leading Japanese ASB one-step, four-station injection stretch blow molding (ISBM) fully automated equipment.

The 10 L PC Square Reagent Bottle is formed using a one-step four-station ISBM process, integrating injection molding, conditioning, stretch blow molding, and bottle removal within a single enclosed system.

From raw material feeding to final demolding, the entire process is conducted under closed and controlled conditions, ensuring high cleanliness, consistency, and product quality.